If you sell one small piece of a business process, sure, go ahead. Once your customer has tens of gigabytes of data in your system you really don't want to shuffle around all of that all the time.

Funny you mention Common 'do what the hell you want lol' Lisp in the same breath as Clojure and APL.

If I ran a one or two person shop and didn't expect to have to grow and shrink the team with consultants at short notice I might use CL or Pharo.