"Branches that do not have a history in the BTB ... are predicted using a static prediction algorithm: Predict forward conditional branches to be NOT taken. Predict backward conditional branches to be taken."
It then goes on to recommend exactly what every optimizing compiler and post-link optimizers like BOLT do:
"Arrange code to be consistent with the static branch prediction algorithm: make the fall-through code following a conditional branch be the likely target for a branch with a forward target, and make the fall-through code following a conditional branch be the unlikely target for a branch with a backward target."
This is why a reduction in taken forward branches is one of the key statistics that BOLT reports.