I haven't worked with trpc, but looking at the docs everything looks to be pretty tightly coupled together In Hono RPC, you just have to replace the fetch api call with the RPC client and you're good to go

For about a year Hono has had mature RPC. So bhvr has a type-safe RPC story without tRPC: export your AppType, import it in the browser, and hono/client gives you fully-inferred calls plus Zod-backed validation — in a ~3 kB helper instead of tRPC’s heavier client and adapters.

You still won’t get auto-generated hooks or WebSocket subscriptions, but for plain REST/JSON the old “hand-rolled fetch” drawback is gone, leaving only edge cases like hooks, real-time, and IDE scalability as the remaining trade-offs.