To live a life that's even remotely healthy we have to dedicate a significant amount of the precious spare time we have just to undo some of that damage.
I do not believe we are predisposed to adopt sedentary lifestyles. As kids most of us are very active, but we are taught to be sedentary. Both academically and professionally we are most rewarded for sedentary activities: doing extra coursework, building your resume. Is it any surprise we develop a sedentary lifestyle when such a lifestyle is most rewarded?