Plenty of simple models in biology that don't model the underlying details provide profoundly generalizable insights across scales. The percolation threshold model explains phase transition behavior from the savanna-forest transition to the complement immune system to epidemics to morphogenesis to social networks.

And the extremely difficult, expensive, and often resultless process of confirming/denying these assumptions is one of the greatest uses of tax dollars and university degrees I can think of, yet, the current admin has taken the perspective that it's all Miasma but also cut the EPA, which by their logic, would stop the Miasma