Yes, an orbital launch probably resets the bathtub to some degree.

I suspect the thermal system would look very different from a terrestrial component. Fans and connectors can shake loose - but do nothing in space.

Perhaps the server would be immersed in a thermally conductive resin to avoid parts shaking loose? If the thermals are taken care of by fixed heat pipes and external radiators - non thermally conductive resins could be used.