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They aren't interchangeable. "i.e." is equivalent to "in other words". "e.g." is "for example".
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The distinction matters because i.e. implies English is the only non-phonetic language in existence.
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> I think in casual speech at this point (at least in my experience) the two are used interchangeably.

How?

They don't mean the same thing.

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Well, the thing is… when you use a borrowed term from a dead language, in writing, it really sounds wrong to cultivated ears. I really had to double-check that sentence to see if I had parsed it wrongly. Not bragging, just saying.

They cannot be completely interchangeable:

“There are white people among us: i.e. me and my father” is totally different from “…: e.g. me and my father”.

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