Physics very much matters to matter.

For development of any information storage systems made of molecules, there must be a supportive development environment.

To even start the process of doing anything like what we see happening in a cell, homeostasis must be achieved first, and not inelegantly, its not good enough to have a complete cell wall if it has no ports for entry and exit of nutrients and waste product, thats also known as a coffin.

Both the walls and the gates and the information / physical systems to reliably exploit those features must be present at the same time to enable abiogenesis.