I took my 6 and 9 year olds to SFMOMA and they played along for about 20 minutes and then started rolling all over the furniture and complaining about being bored, despite my best efforts to engage them in discussions about the art pieces. I got them to settle for a while by playing pencil-and-paper games with them, but then I couldn't look at the art either.
A more extensive talk about ground rules wouldn't have helped. Kids aren't all the same, and most art museums aren't really designed to meet their needs.
(By comparison, they would be happy to spend all day every day at the Exploratorium, and the hardest part there is occasionally pulling one away from some exhibit so that the next kid can get a turn.)