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It’s likely in the order of 10-30, especially with something like ENIG as a finish. If you wanted more cycles, you’d want to switch to a hard gold finish which would likely increase the cost substantially.

This is truly only for a debug port, not anything else.

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Plug an OTG cable in and connect to that, so you don't repeat plug-unplug?
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What about the force transferred by the connector wiggling? I think You'd need a very good mechanical design on the case to make it all work.
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I don't think it's intended for thousands of mating cycles. It's a "free" standard programming/debugging/recovery/configuration interface.
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