I wouldn't mess with enrichment, I'd just go for a breeder reactor, once you start producing pu that is much easier to separate and process into more fuel.
Just start with a big enough pile of natural tubealloy and keep taking away fuel as it builds activity. Experience has shown that disused athletic facilities should be sufficient.
You can also build data centers in far off places, near dams or wind corridors. We are not at the level of desperation to start nuclear programs underground.