The parent article mentions that binding the pages of the first bibles in the correct order, in the absence of page numbers, was an extremely tedious work.
That is why page numbers have invented many years later, exactly as you say, "to help printers not mix up pages".
https://en.wikipedia.org/wiki/Gutenberg_Bible#/media/File:Gu...
Hindsight is 20/20 , lol. There are so many obvious, effective constructs and functions in modern English, we kinda miss the absolute janky mess of hacking and tradition and arbitrary rules and facepalm moments that went in to the last 1500+ years of development, let alone the tens of thousands of years prior.
It's an interesting idea. Remember they printed large sheets containing many 'pages', I think even in different orientations, which were then folded and the ends cut to produce a nice orderly codex for the reader. They were printing in a different order than the one you read in.
I do think they numbered the large sheets or similar, and you can find old books that retain that number, but I don't recall what it is called.