The difference being that compilers and related tools are deterministic, and we can manage the outputs using mathematical proof of correctness.

The LLM's driving this new abstraction layer are another beast entirely.

So I think this question needs to be asked in the context of particular projects, not as an industry-wide yes or no answer. Does your particular project still need humans involved at the code level? Even just for review? If so, then you probably ought to retain human-oriented software design and coding techniques. If not, then, whatever. Doesn't matter. Aim for whatever efficiency metric you like.