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This may sound obvious, but there must also be an enforcement of what's allowed into that sandbox.

I can envision perfectly secure sandboxes where people put company secrets and communicate them over to "the cloud".

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exactly, egress control is the second half of that puzzle. A perfect sandbox is useless for dlp if the agent can just hallucinate your private keys or pii into a response and beam it back to the model provider. it’s basically an exfiltration risk that traditional infra-level security isn't fully built to catch yet.
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Sandbox won’t be enough, distroless + “data firewall” + audit
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Indeed, but a rock solid sandboxing and isolation strategy is step 0.
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