Also, as many might know, blue eyes are the result of a lack of pigment (eumelanin). The iris is translucent, but Rayleigh scattering preferentially backscatters blue photons. Green eyes have some pigment, making them a mix of brown and blue.
I'm not aware of any record of us having done so, but it's absolutely the kind of thing we would do, and there's much more pre-history than history when it might've happened.
https://en.wikipedia.org/wiki/Interferometric_modulator_disp...
(but sort of like chromophores in an octopus or cuttlefish, perhaps).