Diseases are not a monolith, but they do tend to arise and fall in some specific clusters, and that is not "logic", good or bad (too many computer-minded people drag logic into the chaos that is biology), but rather a long-time empirical observation, albeit with some exceptions.
"Anyways, it makes sense that marathoners get CRC because hunter-gatherers probably don't run that much" is bongcloud lalaland tier guesswork.