Obviously you shouldn't follow studies blindly, especially because many studies are poorly conducted and do not replicate, but in general, we know that just following your gut is suboptimal and sometimes dangerous in cases when studies give us clear information.
But my newly adopted dog had hip issues, and I bought a few months worth of a diet supplement in the hopes of doing something meaningf... dammit, it's glucosamine.
They claimed double-blind studies showed decreases in limping in just two months.
Two months, more or less, I stopped seeing him limp by the time we left the dog park. He still does sometimes, but it's rare - not every damn day, by any means.
We aren't that fricking different biologically from dogs in our skeletal attachment system. Maybe it's still a placebo, but it seems to defeat that idea. Maybe enough human issues are based on things that don't translate to dogs - sitting at a desk all day, eating junk food, walking upright... - that it helps them, but not enough of us.
Don't know. These GC supplements have convinced me it's worth my money, and he loves eating them, so he votes 'yes', too.
Unfortunately, the study that showed this used the same medicine my dog had been on, and since it was for epilepsy, I can totally believe that whether I thought it worked had no connection to its effectiveness.