Chrome is big enough that a website owner can't afford a false positive on their malware list, just like they can't afford to have all their email end up in spam for all Gmail users.
Due to their near-monopoly Google also has no incentive to avoid adding false positives to their blocklist - provided they don't accidentally block high-profile targets. And if a CxO is screaming over your shoulder that your website has been blocked, arguments about "false positives" aren't very compelling: they'll just demand you move off the "shitty basement provider" and switch to "proper hosting, like the Google Cloud"...