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Brian May stands out even among that group (well maybe not w/ Les Paul there)

The guy built his own guitar as a teenager and has played it for the rest of his career: https://en.wikipedia.org/wiki/Red_Special

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The podcast "History of Rock in 500 Songs" (full disclosure: I am a devout, slavering fan) provides these on the regular. I was actually smiling when I heard a fairly new song that attempts a really flat, fuzzed out sound because it made me think, "Buddy Holly invented that by accident with a broken speaker". One of the episodes on The Who goes into the Marshall behind Marshall amps in similar detail.

I suppose if I were going to recommend a single episode to Hacker News though, it would be https://500songs.com/podcast/episode-146-good-vibrations-by-... which begins with at least a half hour on the amazing (if not happy) life of the guy who invented the Theremin, Lev Sergeyevich Termen.

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Oh wow! This is incredible...thanks for sharing.
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Ha, you won’t be thanking me once it consumes your life. Join us. We all float down here.
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"Muddy Waters invented electricity!" -- Willie Brown, Crossroads (movie), 1986

https://www.youtube.com/watch?v=LHMv0ORn0hg

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