NMP in particular readily biodegrades in aerobic environments, both in water treatment plants and just in water. Bacteria seem to crack it quickly. It's also not volatile. You have to protect yourself while working with it, but it's not comparable to really nasty stuff, like heavy metals.
I'm not aware of many (non-manmade) barren wastelands on Terra. Even the Empty Quarter has wildlife. About the only place I can think of would be something like the Dead Sea.