This has always been my core Linux desktop woe--there's always, no matter what CPU GPU (including (and most often), no dGPU at all) combo/distro I've used, been sleep wake issues of some variety.
I've had AMD CPUs with both fedora and Ubuntu that would never sleep if they weren't woken to desktop (i.e if not logged in, then allowed to automatically turn off the display) they'd never sleep. On those and any of the machines since, I never get more than a month of uptime without it being unresponsive when trying to wake it or similar, regardless of if Kernel updates have been installed etc.