gentoo (a lot of lines removed):

  $ strace blender-4.4 
  ..
  openat(AT_FDCWD, "/usr/lib64/libpython3.13.so.1.0", O_RDONLY|O_CLOEXEC) = 3
  ...
  openat(AT_FDCWD, "/usr/lib/python3.13", O_RDONLY|O_NONBLOCK|O_CLOEXEC|O_DIRECTORY) = 12
  ...

No issues with plugins