I can’t find the tweet from Mario (the author), but he prefers the Typescript/npm ecosystem for non-performance critical systems because it hits a sweet spot for him. I admire his work and he’s a real polyglot, so I tend to think he has done his homework. You’ll find pi memory usage quite low btw.
Also python ones would also allow self modifying. I'm always puzzled (and worried) when JS is used outside of browsers.
I'm biased as I find JS/TS rather ugly language compared to anything other basically (PHP is close second). Python is clean, C has performance, Rust is clean and has performance, Java has the biggest library and can run anywhere.