The "whole region" fears Iran more than they hate the US, judged by their behavior.
It is the Saudis and the other monarchists and oligarchs that have decided to sell out their countries to the US and Israel. They fear their own people more than anything else.
Iran is the only country in the region who has supported the Palestinians. Everyone else has looked the other way. Iran has not invaded any other country. It is Israel that keep the region in a constant state of war.