If you have to wait overnight because the model is offloading to disk, that's a model you wouldn't have been able to run otherwise without very expensive hardware. You haven't really lost anything. If anything, it's even easier to check on what a model is doing during a partial inference or agentic workload if the inference process is slower.
This exact problem exist for rendering, when you realize that after a long render an object was missing in the background and the costly frame is now useless. To counter that you make multiple "draft" renders first to make sure everything is in the frame and your parameters are properly tuned.