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> Its breaking a bunch of my systems that are all launched with `uv run`

From a security standpoint, you would rather pull in a library that is compromised and run a credential stealer? It seems like this is the exact intended and best behavior.

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You should be using build artifacts, not relying on `uv run` to install packages on the fly. Besides the massive security risk, it also means that you're dependent on a bunch of external infrastructure every time you launch. PyPI going down should not bring down your systems.
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This is the right answer. Unfortunately, this is very rarely practiced.

More strangely (to me), this is often addressed by adding loads of fallible/partial caching (in e.g. CICD or deployment infrastructure) for package managers rather than building and publishing temporary/per-user/per-feature ephemeral packages for dev/testing to an internal registry. Since the latter's usually less complex and more reliable, it's odd that it's so rarely practiced.

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There are so many advantages to deployable artifacts, including audibility and fast roll-back. Also you can block so many risky endpoints from your compute outbound networks, which means even if you are compromised, it doesn't do the attacker any good if their C&C is not allow listed.
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Are you sure you are pinned to a “known good” version?

No one initially knows how much is compromised

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Take this as an argument to rethink your engineering decision to base your workflows entirely on the availability of an external dependency.
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That's PyPI's behavior when they quarantine a package.
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That's a good thing (disruptive "firebreak" to shut down any potential sources of breach while info's still being gathered). The solve for this is artifacts/container images/whatnot, as other commenters pointed out.

That said, I'm sorry this is being downvoted: it's unhappily observing facts, not arguing for a different security response. I know that's toeing the rules line, but I think it's important to observe.

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known good versions and which are those exactly??????
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