<esc>S
Esc exits insert mode (of course) and capital S erases the line and puts you in insert mode at column 0 (just like in (n)vim, right?).
Like I said, maybe I configured that? But 'S' is standard vim-stuff... (I'm not able to double check my config at the moment).
[Edit: right after hitting submit I realized that my way is perhaps "arguably" simpler because I do have to hit shift to get capital S. So I'm also hitting three keys...]