Yes, if the packages are pure JS logic (no native C++ addons, no Node-specific I/O like child_process or net). The script option auto-resolves imports from node_modules/ and bundles via OXC. Node compat APIs (process, path, fs, os, Buffer) are available with apis: [:browser, :node]. For packages with native .node addons, there's load_addon/3 which supports N-API.