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Early research links them to serious risks, including increased risks of heart attacks, stroke, and mortality, alongside potential inflammation, metabolic disruption, and reproductive harm.
https://med.stanford.edu/news/insights/2025/01/microplastics...
> Animal and cellular studies have linked microplastics to biological changes including inflammation, an impaired immune system, deteriorated tissues, altered metabolic function, abnormal organ development, cell damage and more. A recent large-scale review of existing research by scholars at the University of California, San Francisco, concluded that exposure to microplastics is suspected to harm reproductive, digestive and respiratory health and suggested a link to colon and lung cancer.
> More than two years after the procedure, those who had microplastics in their plaque had a higher risk of heart attack, stroke and death than those who didn't.
> So far, his research shows that these plastics can get inside cells and lead to major changes in gene expression. "These findings suggest that the particles contribute to vascular disease progression, emphasizing the urgency of studying their impact," he said.
> Children, whose organs are still developing, could be at higher risk of harm
https://pmc.ncbi.nlm.nih.gov/articles/PMC10151227/
> Thus, chronic exposure to low concentrations of microplastics in the air could be associated with respiratory and cardiovascular diseases depending on an individual’s susceptibility and the particle characteristics.
> The results of cellular and animal experiments have shown that microplastics can affect various systems in the human body, including the digestive, respiratory, endocrine, reproductive, and immune systems.
> In addition, microplastics interfere with the production, release, transport, metabolism, and elimination of hormones, which can cause endocrine disruption and lead to various endocrine disorders, including metabolic disorders, developmental disorders, and even reproductive disorders (i.e., infertility, miscarriage, and congenital malformations)