Propeller can’t really do many instruction level modifications due to how it works (constructs a layout file that then gets passed to the linker).

BOLT could do this, but does not as far as I’m aware.

Most of vectorization like this is also probably better done in a compiler middle end. At least in LLVM, the loop vectorizer and especially the SLP Vectorizer do a decent job of picking up most of the gains.

You might be able to pick up some gains by doing it post-link at the MC level, but writing an IR level SLP Vectorizer is already quite difficult.