I didn’t encounter too many of those back in the day, I think because there was the VBL task mechanism for synchronizing with screen refresh that made it easy to avoid using instruction loops for timing.

Much more common in my experience was the assumption that the framebuffer was 1-bit, but such games would still run on my IIci if I switched to black & white—they’d just use the upper left 3/4 of the screen since they still paid proper attention to the bytes-per-row in its GrafPort.

Could be that by the time I was using a Mac II though that all the games that didn’t meet that minimum bar had already been weeded out.