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You’re confusing a few of the issues here. This isn’t an interstate commerce case, it’s a tax power case, which does reflect on the NFA but not on Wickard v Filburn or civil rights. The important aspects of federal civil rights law aren’t legally justified by the commerce clause either.

Though I would gladly see Wickard v Filburn overturned. Commercial regulations already vary by state, and the US would still be more cohesive than the EU is today, but the amount of water that flows through my showerhead doesn’t have to be a concern of the federal government. In fact, we don’t even need Wickard v Filburn to be a more cohesive federation than Canada, which doesn’t even have free trade between provinces.

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> No EPA, no federal minimum wage, no forced integration, reduced civil rights, only direct interstate commerce being regulated.

States can still do civil rights etc.

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A quick look at our history shows why this was important at a federal level.
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Another quick look at your history also tells you why a strong federal government has downsides. Life is full of compromises, but I like me some subsidiarity.

https://en.wikipedia.org/wiki/Subsidiarity

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Seems to have worked rather well though.
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If it works so well, perhaps delegate authority even more centrally. To the UN or so?
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I mean you said it yourself, it's a compromise. Giving the states free reign to terrorise their populations didn't work out so great. The relatively strong federal government of more recent times however seems to have worked out not so badly. Now there's a retarded paedohpile in office starting random wars and of course all bets are off. The US political system actually probably is quite shit, but I don't think it's about centralisation vs decentralisation, but electing an unaccountable king every 4 years is just a retarded and easily exploitable system.
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> Giving the states free reign to terrorise their populations didn't work out so great.

Be careful not to be anachronistic. When the US was a young country, before telegraphs and railways were widespread, most people's primary interface with the government was perhaps their municipality or at the highest level perhaps their county.

> The relatively strong federal government of more recent times however seems to have worked out not so badly.

I am not so sure. Different people in different parts of the country have different preferences. Much easier to satisfy them, if you don't centralise too much.

> [...] but electing an unaccountable king every 4 years is just a retarded and easily exploitable system.

Much better to elect 3,143 kings, one for every county. If you don't like the one your neighbours (and you) voted for, just move to the next town over.

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"just move" is not always a simple act for the most vulnerable in society.
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Moving counties is almost infinitely easier than moving countries, or replacing the entire federal bureaucracy to your liking (instead of the liking of that other guy).
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You’re right, it’s much easier to replace the entire federal bureaucracy.
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