Maybe a severe enough snow storm? Even then we’re in Goldilocks territory for the storm to be unsafe for bikes but safe(ish) for cars.
The biggest factor is that people simply will not get on their bikes in severe enough weather. At least not in most places. Maybe in the Netherlands they’ll bike in a blizzard.
Any weather where the wind is >15mph will be safer in a car. Hail. 100 F days. Thunderstorms. I love walking and public transportation but holy hell the thought of biking in some of our Texas weather is horrifying.
Not to mention that my 6yo and 9yo are much safer in my car than cycling through inclement weather! Not everyone is a single individual with no children! Holy hell, the trip from a kid's bday party to my house two weekends ago would've been deadly for my kids, but in a car, the weather wasn't an issue.
Hail comes to mind. Lightning possibly (I believe cars are much better insulated against lighting strikes). High winds could easily push bikes around / knock them over where cars just keep going.
We drove our van through a forest fire (Cedar Creek Fire - a BIG one) and got a bit of smoke, but otherwise, just fine. No way would I have attempted that on a bike - the increased aerobic activity alone (to say nothing of embers / ashes / etc) would have probably caused crazy amounts of smoke inhalation / death.
And there is a reason drivers hate SOME bikers - here in CA, many simply refuse to follow the rules of the road. My light turns green, and 5 seconds later, some biker comes rolling along in the perpendicular direction - I almost hit him. This kind of stuff happens over and over. I am very fond of bikers when they follow the rules - I bike sometimes too.
Riding a bicycle while wearing an unpowered respirator/face mask is surprisingly easy, especially if it has an exhalation value. It does restrict breathing somewhat, but breathing isn't usually the bottleneck when you're cycling. This might even be the optimal way to escape a fire if the roads are congested.