As a dev manually typing I loved tailwind for sure, with LLMs not so much, and bootstrap in particular nails it the best IME. and yeah one can customize bootstrap quickly to look however it should, just tell your frontier LLM of choice your wishes.
I don't ever recall hearing about the specific, tangible benefits tailwind brings. Just a loose "it's faster", or "it's easier". It just feels like one of those things, in front end development, that are just hype-driven rather than actually bringing any ostensible benefit.
I'm not a big tailwind fan, but keeping styling in a separate file feels like a net negative