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500 years is as arbitrary a number as 79 is.

A Craig Venter that lives (a healthy life) to 158 is quite likely to accomplish at least 1 more great thing than one who lives to 79.

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More likely that he would live most of those years with compounding mental and physical health issues, quality of life degrading to the point where most would wish for death instead.
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What an un-hacker ethos: the idea is to continuously fix problems so that, if anything, quality of life improves from year to year.
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