I can't find an official source, but I suspect the blast radius isn't limited to the AZ.
I have systems running in us-east-1, and over the course of the incident, I noticed unexplainable intermittent connectivity issues that I've never seen before, even outside of az4.
spent the evening looking at SLI graphs waiting for the region to blow up but it never did. only a few envs across many had some degraded EBS vols in the single AZ. it was absolutely a single az (use-az4).