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You just send packets to the other party's address and they send packets back to yours. Both parties know their address and you don't need a relay in the middle.
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It's not really relevant in this case since one endpoint is a massive server farm.
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It is because most of their complexity is in routing packets. With IPv6 you can just have the thing handling the conversation directly addressable by the client. The last 64 bits of a v6 let you have billions of instances in a region.
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