> Maybe use voice recognition that uses lip-reading through a camera to launch or modify?
This feels like the result of a competition to design the worst possible user interface. To about 5% of people it might be an accessibility feature, to everyone else it's worse, and people with beards, marks, or dark skinned faces are going to find it a disaster.
True, it's not a good solution and there is Subvocal Recognition (SVR) that detects electrical signals in the neck or jaw using pads. Hall effect keyboards are pretty good in terms of sensitivity I find.
Lip reading by HAL was also a disaster for Frank Poole.
Maybe a large screen that can easily be flipped vertical/horizontal would work well. People already do it with the their smartphones - why not stationary screens? Have the OS detect when it happens so it can make any predetermined layout changes. Maybe have it rotate using a small motor? Cable connections into a base unit to avoid entanglement.
In terms of screens - I think two volume dials to adjust for brightness and another one for blue-light would be ideal. It should be super easy to do at a hardware level. On 24 hour programs if really pedantic. Maybe an external "volume dial" pad that can be plugged into a USB-C would be suffice and it could have a light and movement sensor as well to take a computer out of (and into) suspend and set the desired brightness according to the environment.
There are rechargeable closet lights that already have movement and light sensors - just need to adapt it to a screen.
Good news: all of this except the motorization is already available from Dell and others. Common office setup. I often see people with one screen in portrait format for reading documents.