Not having a multi-tenant system is something else. There you're trying to be protected from other customers, not the provider. Excluding other tenants still wouldn't protect you against the provider, especially on systems with proprietary and potentially exploitable ring -1 hardware they could already be silently in control of even when the entire machine is allocated to you.
Meanwhile for anything on the scale of an organization, having physical possession of the machine yourself isn't that expensive. People got hoodwinked when virtualization first came around because they compared the cost of having a mostly-idle physical server for each of their applications to having that many cloud VMs, and the cloud VMs were cheaper, but that isn't the right comparison. You don't compare having 100 physical machines to having 100 VMs, even if people used to use 100 physical machines for that in 2005. You compare it to having three physical machines that can each run 100 VMs, and then having physical possession of your own hardware is frequently less expensive.
If I were to be CTO of a brand new company today, I’d probably just colocate my own servers with K8S. Much cheaper and much lower latency. 2x 1TB RAM servers with 3x 8TB high speed U.2/U.3 drives each would last years.