Nicotine has both positive and negative effects but the impact on hypertension can cause pretty serious adverse health problems for some heavy users.

absolutely not true

they erode your gums

and the accelerated rate of nicotine absorbtion probably has side effects we do not yet understand

Yeah, but nicotine itself can still be problematic for mental health. It really depends on what you consider an "adverse problem".

I had been using the pouches for a couple of years now, and the unbearable anxiety from its nonstop use caused me to slow it way down. I went from a can a day to less than a can a week. I had already quit all other forms of nicotine before the pouches. What a wild ride.

Because the anxiety is unlikely to just be from nicotine alone, I also got myself into somewhat better shape to cope. Maybe some anxiety is healthy if it drives better choices, but it still feels awful. I'm now glad with my current state, but I would not recommend this path to here.