As a lefty I never had any problems adapting to a right hand mouse and actually find the keyboard to be better suited as a "left hand" activity and would have a hard time switching it up.
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replyLiving with laptops with touchpads for a couple of decades as a righty, I can use a touchpad perfectly fine with either hand, but a mouse is still right handed for me.
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replyI have switched between left and right mouse every few years when I was younger, just to see what works best for me. I could adapt to both, even though I can only write and draw with my left hand. I have settled with left-hand mouse because I feel like I can be a bit more precise for graphical works and shooters.
replyWith the trackpad on my Laptop, I switch quite frequently and haven’t yet noticed any difference in precision. The movement is very different than mouse or pen control though and comes more from individual/multiple fingers instead of the whole hand or arm, so I guess that explains it.
I mouse right-handed because it’s convenient, but I still naturally default to doing any novel task left-handed. It’s not a matter of fine motor skills, you can learn to do anything with either hand if you decide to, it’s just an unconscious preference.
replyWith modern controllers the main joystick/thumbstick is on the left side. People are using both hands for fine control in different circumstances.
replyKeyboard is also both hands equally used. With handwriting less common, I wonder if people are shifting mostly towards using both hands equally now.
replyI used right all the time. Got RSI.
Now I use left at work all day, and right at home when gaming.
replyAt work, I don't use a left handed mouse. Just those cheaper but common symmetrical ones. And I don't bother changing handedness. I just pick up the mouse and put it to the left of the keyboard.
shrug It works.