All ADCs I have looked at document that they can't represent the positive full scale. For instance, for an 8 bit ±1 V ADC, -128 represents -1 V, +127 represents 127/128=0.99219 V. The transition from 126 to 127 happens at 1.5 LSB from the positive full range. 1 LSB difference represents 1/128 = 0.00781 V difference, and not 2 / 255 = 0.00784 V.

But if you actually care about what the voltage (and uncertainty) is, most of this is difference is mostly pointless, you're reference will have a bias, there are linearity errors and so on. 1 LSB will not match either the 1/128 or 2/255, you will need parameters to compensate for it.