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My personal headcanon is that every Star Trek series takes place in its own universe, parallel to the others. That's the only way it makes sense that Data as an android is viewed as a unique being when in TOS Harry Mudd was grifting an entire planet of fembots and no one batted an eye.
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Roddenberry did not want TNG or even the original-cast movies to maintain tight continuity with TOS because he thought a lot of stuff in TOS was hokey and campy. He wanted the movies and TNG to set a more serious tone in a more believable universe.

TNG/DS9/VOY/ENT and the movies were all fairly explicitly in the same universe and with characters referencing things that happen in other series and a reasonable effort at continuity.

A example of this is the ENT episode where they meet the Ferengi. It had been established as cannon already that Picard made first contact with the Ferengi on USS Stargazer like 150 years later, so they just added this scene where the ENT characters memories of the event was wiped, so that the "official first contact" could still be Stargazer.

The Neutrek stuff isn't in the TNG universe for a variety of reasons, although I think part of it is they didn't want to put the work in to maintaing continuity. None of the TNG era producers or show runners were involved and nobody they wanted to hire really knew the lore.

That being said I don't think there's really a continuity problem with Mudd's androids because he didn't make them they were from another galaxy, and the fembots weren't really implied to be sentient except when they had a human brain put in them.

TNG kept "accidentally" making sentient machines from Data/Lore to the drilling robots, the nanites, and Professor Moriarty. It does seem strange after all that they still considered Data unique.

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