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Hmmm, well let’s take it one step lower. What do you think of organelles such as ribosomes? Do you disagree with the assumption that those are machines? They seem directly analogous to the jacquard loom or a CNC machine to me.
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Yes again, ribosomes have nothing in common with machines, that are built and designed by humans.

The ball is in your camp to provide solid reasons to believe why they should be grouped together, when one is a deeply complex interrelated dynamic system (in fact, arguably the most complex system we know of) evolved bottom up over billions of years that we only very partially understand and cannot fully explain or document, and the other something entirely planned, designed, and produced by humans in which every component is finite and accounted for.

The argument boils down to “well the vibes kind of match to my taste, and it’s the best analogy I have in my analogy toolkit”, which is just not serious reasoning.

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I think ribosomes have a lot in common with machines. They use energy to accomplish a task (assembles proteins). This would seem to put them in the same category as artificial molecular machines like rotaxanes. I don’t think there’s a huge gap in our understanding of how either systems identically functions independently. Yes, ribosomes exist as part of a larger context, but they can be removed from that context pretty easily and understood as individual molecules quite extensively.

In your view, can machines even exist that haven’t been created by people, definitionally? I, personally, don’t see the relevance of intent but that seems to be the only distinguishing factor here.

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replication: https://en.wikipedia.org/wiki/Quine_(computing)

autonomous replication: https://en.wikipedia.org/wiki/Computer_worm

nb that writing your own quine remains in general terms a fun and challenging exercise in many programming languages, but not python.

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We are talking about physical replication, please let me know when a computer worm can turn my laptop into 2 laptops

Otherwise you’re just arguing that Sims are totally alive because Sims can make baby Sims.

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The assertion is not that cells are machines built by humans (obviously false), merely that they are machines. Which they pretty clearly are, unless you assume the supernatural.
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There is no need to assume the supernatural. They are machines based on what? By definition, a machine is something build by humans, or any intelligent life form (because we extend the definition from our own experience as self defined 'intelligent life forms'). Living organisms and machines do share traits under our current frame of reference in modern science. But that doesn't mean cells are machines. The right framing would be 'cells exhibit behavior and certain internal relations that we can conceptualize them as machines', which is different from 'cells are machines'.
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By what definition?

Anyway, seems like an argument over said definitions rather than the underlying characteristics. The relevant question is whether they're purely physical objects behaving according to rules, which is being described as "machine," or whether there is something beyond that. Current understanding is contradictory: all indications are that cells and bodies are purely physical objects, except that there is this phenomenon of subjective experience which doesn't fit with that at all.

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What exactly is there about cells that's inconceivable to replicate or synthetize? "I cannot conceive it" is a fallacy, an argument from incredulity. Trying to disguise it by draping it in the passive voice does not change that fact.
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Nothing. It is just that they are so incredibly complex, that after +100 years of research we still don't know how they work or why. Will there be a time when we finally understand them 100% and could replicate them? Could be. That does not make them machines in any case, and the fallacy of thinking that mind/consciousness can emerge from machines will still be there.
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