What are some common hold-ups you know of? I don't program but have still used GNU/Linux on my main machine for over a decade now. It can browse the web, play games, listen to music, watch TV and movies, you can draw, you can edit video, you can stream to Twitch.
replyAdobe.
replyGames with kernel anti-cheat.
Office 365 (I think this mostly applies to overly complex Excel spreadsheets with lots of macros? There are also a bunch of people here who say LibreOffice has bad UI, or that they (somehow?) have documents that are complex enough that LibreOffice can't display them properly. Openoffice is somewhat better on those fronts, but neither are good enough if it's for actual work).
It's mostly professional software that is the issue. CAD, CAM, BIM, GIS, DAW, PLC, accounting, graphic arts, etc. etc.
replyMostly hardware with previously-shipped drivers,
replyand no updates planned.