Modern medicine sort of requires us to suspend the idea that we can know everything happening in our body at any given time. If we could develop a diagnostic technique to instantly determine if shapes in our bodies are malignant or benign something like frequent full body scans could be interesting, but they really just introduce noise right now.
The diff can be meaningless as well. All sorts of benign things develop with age.
The resolution is the problem. You can't do the type of cytology and histology needed to understand all disease with just scans.