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I can't see how ultrasonic tomography can actually get anywhere near the resolution or penetrative depth that MRI can have.

Also The other thing I am unsure of is what the health effect of dumping you into an industrial scale ultrasonic cleaner. For example you can have doppler to measure blood flow in real time, but you can't do that for early pregnancy because of some health reason or other.

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I help engineers design traditional scanners (Philips, GE, Siemens, etc). To be frank, this statement stinks like utter pig shit.

Some PE bro preaching miracles about a technology that I am sure they are in some way invested in making profit from does not convince me of it's legitimacy. My base instincts, from the unfortunate experience of working daily with PE bros, tell me the opposite in fact. It gives déjà vu of the Theranos hysteria.

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The X post is obviously biased, but I couldn't spot any obvious scientific mistakes in the actual announcement video.

Someone else linked to this preprint which seems related [1]. Would you take a look and say whether it seems legitimate?

[1] Whole Cross-Sectional Human Ultrasound Tomography” https://arxiv.org/pdf/2307.00110

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The authors report explicitly state that the system's resolution does not match clinical CT or MRI. The elevational resolution is 15–25mm, meaning each slice is effectively a thick 2D section rather than the fine isotropic 3D volume MRI provides. MRI also delivers far richer soft-tissue contrast; this device produces only three contrast types (reflectivity, speed of sound, attenuation), and because it uses a low 1MHz frequency, the reflection images come primarily from tissue boundaries rather than from internal tissue texture.

I could see this being valuable for adipose tissue mapping or fatty-liver monitoring at a large scale, as the machines would be significantly cheaper, but this isn't some revolutionary magic bullet like the Twitter post is insinuating.

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As someone in the medical imaging field, are you aware of anyone working on passive sonar for medical imaging? I'm curious, as it's something that I've always thought would be fun to work on.
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For context I'm in engineering consultancy, so by no means an expert but I probably have enough experience to be on the other side of the Kruger curve dip.

Passive sonar in the naval sense means listening only, not emitting. Do you mean imaging that relies solely on acoustic energy already present and emitted by the body? If so, then generally no. You have two types of "passive" imaging. First would be hardware-passive, as in MR elastography (most common), where the patient wears a transducer pad, and vibration is actively generated by a driver. You've then got algorithmically-passive, which is more analogue to passive sonar, reconstructing tissue stiffness from ambient broadband vibration without the emitted probing pulse, but that is very much entirely academic. I guess the question would be, why is it worth pursuing when you have something like optical coherence elastography (OCE) for non-invasive profiling. Doing it using noisy ultrasound method becomes redundant. There are other methods, but the outcome is the same.

Generally (this is true for all systems, not just humans) you need to induce energy into it to more effectively measure it's output. Think of it like a bell - if I want to hear the note it produces, it's much easier to hear what this is if I ring it with a hammer. Granted, it will be "passively" resonating to a point where, with a sensitive enough sensor, I could probably pick up the output without the hammer - but that is a pointless problem to solve. I could hit a bell with a soft hammer a million times over without causing damage to it. The lifetime of the person hitting it with a hammer is far shorter than the accumulative damage to the bell before it breaks. The same is true for humans. You could effectively run a very low-energy, 60Hz vibration through a person (which is how the pads work) for multiple lifetimes before it would cause significant damage, so there comes little point in solving that problem. As such, true "passive" imaging is functionally pointless if your outcome is "safely image a patient". You're overengineering your solution to solve a problem that is only relevant if your patient was planning on living for 1000+ years.

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What does PE mean?
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private equity
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