If the instance goes down, the network stays up and continues to work, minus only the accounts on mastodon.social. This is not the case on bluesky afaik. They got DDosed a few months ago and the whole network was down because of it. https://news.ycombinator.com/item?id=47802330
In ATProto there aren't 'instances', and its technically 'decentralized' but theres really only bluesky.