Most people can pick up calculating subnets in their head in ipv4 pretty quickly and ipv4 addresses are easy to memorize on accident. My brain turns to mush as soon as I start seeing hexadecimal characters in addresses.
you can send a packet from an extended address host to a vanilla v4 host if you map the address space into a range like you suggest..but that v4 host just has no way of sending a message back..so its kinda useless