Imagine two computers A and B. A has two NICs, A1 and A2. B has B1 and B2. So 4 NICs total. You connect directly A1 to B1 and A2 to B2 with crossover cables. You then route all the traffic from A to B over A1 to B1 and all the traffic from B to A over B2 to A2.
Why do you do all this? To avoid collisions and the loss of effective bandwidth from back-offs.
It only really works with 2 computers because if you add a 3rd, now you need 12 NICs instead of 4 for unidirectional point-to-point connections.